Palazzolo Acreide is a town and comune in the Province of Syracuse, Sicily. It is 43 kilometres from the city of Syracuse in the Hyblean Mountains. It is one of I Borghi più belli d'Italia. The area around Palazzolo Acreide has been inhabited since ancient times. In the 10th-11th centuries BC, the Sicels lived here in small villages. The town occupies the site of the ancient Akrai, founded by Syracuse around 664 BC. The city was important as it controlled the paths of communication between the towns on the southern coast of the island. According to Thucydides, the Syracusans defeated the Athenians here in 413 BC.