The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...
Post-mortem examination of a mouse heart shows a clear delineation in blue where TREE gene enhancer sensed and responded to tissue damage of a heart attack. photo - Ken Poss Lab, Duke University ...
Enhancers, which are thought to turn genes on by coming into physical contact with gene promoter regions through transiently forming a complex, were discovered about 45 years ago. More recently, in ...
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are ...
Though almost every cell in your body contains a copy of each of your genes, only a small fraction of these genes will be expressed, or turned on. These activations are controlled by specialized ...
A team of researchers unveils a novel, key aspect of enhancer-mediated regulation of gene expression and proposes a mechanism that explains the tight connection between gene enhancers and promoters.
Scientists at the Massachusetts Institute of Technology (MIT) have invented a new single-cell nascent RNA sequencing technique that lets them observe the timing of gene and enhancer activation in ...
The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...