Genetic prediction of common diseases is based on testing multiple genetic variants with weak effect sizes. Standard logistic regression and Cox Proportional Hazard models that assess the combined ...

Reduced rank approximation of matrices by Householder-Young methods is shown to be equivalent to fitting of a bilinear (multiplicative) model and to projection onto an optimally chosen subspace. The ...

This is a preview. Log in through your library . Abstract It is a widely held belief in public health and clinical decision-making that interventions or preventive strategies should be aimed at ...