Replicating the amniotic sac The team at the Crick created a new 3D model -- called a post-gastrulation amnioid (PGA) -- which closely resembles the human amnion and other supportive tissues after ...

Microscopy image of a PGA at day 8 showing the early tissues supporting the embryo, including the amniotic sac and the yolk sac-like structures, surrounded by (extra-embryonic) mesoderm tissue.

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...