RNA granules, sites for the storage, transport, and regulation of RNA molecules within cells, are transported along axons and then translated locally, far from the cell body. Recent studies suggest ...

A collaborative effort between engineers and biologists at the Hong Kong University of Science and Technology (HKUST) has uncovered a neuroprotective mechanism in spinal cord injury (SCI), shedding ...

Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells, according to a novel study. Myelin is an insulating sheath around axons -- the processes ...

Axonal degeneration is a key early pathogenic driver of amyotrophic lateral sclerosis and other neurodegenerative diseases. Activation of calpain-2 (CAPN2) is thought to be the critical effector ...

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins. It enables rapid conduction of electrical signals and supports ...

Sironax Ltd. has discovered (+) hydrolase SARM1 (SAMD2; MyD88-5) inhibitors reported to be useful for the treatment of amyotrophic lateral sclerosis, diabetic neuropathy, multiple sclerosis, Parkinson ...

Thought LeaderDr. Federico Dajas-BailadorHead of Axon Biology Lab University of Nottingham UK After a recent visit to ELRIGs Drug Discovery 2023, News-Medical sits down with Dr. Federico ...