Problems with the brain’s ability to ‘prune’ itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today ...

A new study from Austrian researchers suggests the brain begins life with an overly dense and disorganised network of ...

Adolescence is widely thought to be a time when the brain trims away excess neural connections, refining circuits through synaptic pruning. New research now suggests this view may be incomplete.

White blood cells called neutrophils act as factories for C4A, linking peripheral immunity to schizophrenia and synaptic ...

Many disparate conditions, such as depression, phobias and attention deficit hyperactivity disorder (ADHD), may have the same underlying cause: a delay in “pruning”, a process in which unneeded ...

Dense at birth: Mouse hippocampal networks start heavily interconnected, contradicting the 'blank slate' theory of brain development. Pruning over time: Connections become sparser and more organized ...

If you scroll through TikTok or Instagram long enough, you’ll inevitably stumble across the line: “Your frontal lobe isn’t fully developed yet.” It’s become neuroscience’s go-to explanation for bad ...