The drugs now allow a detailed first assessment of CaMKII functions in any given system that's accessible to a wide range of scientists. Previous studies by Bayer's lab revealed that inhibiting CaMKII ...
Yet CaMKII is present in nearly every other cell. The review offers insights into the protein for those who don't study it fulltime, providing tools to fill in the gaps in knowledge about how the ...
Neuroligins are postsynaptic cell adhesion molecules that are important for synaptic function through their trans-synaptic interaction with neurexins (NRXNs). The localization and synaptic effects of ...
Forty years since its discovery, much remains to be discovered about an enzyme called CaMKII that plays a key role in shaping learning and memory in the brain. Now Roger Colbran, Ph.D., graduate ...
To form and cement memories, the synapse must restructure itself, breaking down some proteins and rebuilding new configurations. The proteasome, which mediates the breakdown process, migrates into ...
Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation. Their study, ...
The health impacts of a complex protein that plays a major role in the development of Alzheimer's disease and heart conditions can be lessened by three kinds of drug inhibitors, according to ...
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