To form and cement memories, the synapse must restructure itself, breaking down some proteins and rebuilding new configurations. The proteasome, which mediates the breakdown process, migrates into ...
Figure 1: sLTP induces rapid, persistent, and largely spine specific TrkB activation. Figure 2: TrkB activation during sLTP depends on NMDAR–CaMKII signalling and postsynaptic BDNF. Figure 3: ...
The present study investigated the effect of long-term (15 mg/kg for 15 days) and acute (15 mg/kg, single administration) treatment with desmethylimipramine, a tricyclic antidepressant drug, on ...
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