During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their first steps toward a lineage commitment. Jacob Hanna, a ...

The mystery of early embryonic communication is starting to be unraveled thanks to a new stem cell-based model.

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

The stem cell-based embryo model and actual human embryos share many characteristics but are distinctly different. However, internationally, not everyone agrees on the definitions and what we should ...

Technological, ethical and legal issues have limited the understanding of the early stages of embryonic development in humans, despite its importance in basic developmental biology and reproductive ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development—including the production ...

Around eight days after fertilization, the human embryo implants in the endometrium (the tissue that lines the uterus). After implantation, it enters a developmental phase that is not well understood ...

Research improves upon a popular experimental model of mammal development and in doing so, reveals more of the inner workings of a critical period during the formation of an embryo. Research from Ph.D ...

University of Pittsburgh researchers have developed a new embryo-like model derived from adult cells that replicates key features of early human development, including the generation of blood cells.