Scientists at the University of Southern California (USC) have developed an organoid model of the human brain that generates granule cells and Purkinje neurons—two major cell types found in the human ...

The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or ...

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model ...

Scientists have developed a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for ...

Purkinje cells were discovered by Jan Evangelista Purkyně in 1839 and famously illustrated by Santiago Ramón y Cajal in 1899. This Ramón y Cajal drawing shows cerebellar Purkinje cells (A) and granule ...

Differences in brain shape between a present-day human (left, in blue) and a Neanderthal from La Chapelle-aux-Saints (right, in red). Source: Max Planck Institute for Evolutionary Anthropology/Simon ...

From before birth through childhood, connections form between neurons in the brain, ultimately making us who we are. So far, scientists have gained a relatively good understanding of how neural ...

Genetic maps of the development of cells in the cerebella of human, mouse and opossum shed light on ancestral and species-specific cellular and molecular characteristics of cerebellum development. The ...