Histoplasmosis is a fungal infection that can cause swelling, inflammation, and, sometimes, small semi-opaque or calcified nodules on the lungs. However, histoplasmosis does not always cause symptoms.

Smoking can cause lungs to look blackened, inflated, and inflamed, but some of the damage is reversible. Depending on the extent of the damage, it could take years for your lungs to regain a healthy, ...