TRPML1 is a promising target1 for Parkinson’s disease treatments and identifying translational biomarkers will help confirm target engagement ...
Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...
Find out how AI influences drug discovery, enabling earlier predictions and reducing the risks in clinical development.
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...
A significant portion of disease-relevant proteins remain “undruggable” by traditional therapeutic approaches, representing a major hurdle in drug discovery. Targeted protein degradation (TPD) is ...
Most patients with gastric cancer are diagnosed in advanced stages of the disease. Target identification and unveiling the molecular mechanisms behind it are crucial for this field.
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