This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected ...

Epigenetics is a rapidly growing field of study that focuses on the heritable changes in gene expression that occur without alterations to the underlying DNA sequence. These changes are caused by ...

Maternal prenatal stress related to natural and human-made disasters can lead to epigenetic modifications in offspring, ...

Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

Children with a family history of type 1 diabetes (T1D) have an increased risk of developing the disease. However, children born to mothers with T1D are less likely to develop the disease than those ...

Type 1 diabetes is an autoimmune disease in which the immune system destroys the body’s own insulin-producing beta-cells in the pancreas, leaving patients with a lifelong dependency on external ...