Homologous recombination is central to the repair of DNA double-strand breaks and the rescue of stalled replication forks. A pivotal intermediate in this process is the Holliday junction, a four-armed ...
In the world of biomolecules, none is more iconic, nor more versatile, than DNA. Nature uses the famous double helix to store the blueprints of all living forms, drawing on a four-letter alphabet of ...
The orange wheel shows the circular chromosome or genome of E. coli bacteria. The spikes indicate where a molecular intermediate in DNA repair -- four-way DNA junctions -- accumulate near a reparable ...
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