You have full access to this article via your institution. To recreate the complex multicellular interactions of one region of the human liver — the ‘periportal’ part — in a dish, we developed a ...

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks associated with exposure. In recent years, as part of efforts to reduce animal ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...