A study questioned the use of brain volume loss as a clinical trial endpoint in PPMS after finding a weak link to disability ...

Share on Pinterest Researchers say brain lesions don’t appear to be connected to severe disability in multiple sclerosis. SeventyFour/Getty Images About 1 million people in the United States live with ...

Brain volume loss is a key marker of degeneration in multiple sclerosis, correlated with future disability progression. Ponesimod, alemtuzumab, teriflunomide, ozanimod, and fingolimod significantly ...

"We plan to analyze these MRI structural measures longitudinally to determine if changes in brain volumes or lesion burden over time contribute to fatigue trajectories. More broadly, we might ...

For decades, multiple sclerosis (MS) has been defined primarily by its symptoms, rather than its underlying biology. Now, a new study aims to challenge that approach, presenting evidence that MS may ...

In the human brain, neurofilament light chain (NfL, shown in brown) is seen in brain cells and the neural wires that connect them. UCSF researchers found NfL in the bloodstream of patients who would ...

Multiple sclerosis, a complex neurological condition affecting nearly 3 million people worldwide, has long been characterized by its elusiveness. Even as medical imaging technology has advanced ...

Multiple sclerosis (MS) is best known for the physical symptoms it can cause, such as numbness, weakness, spasticity, and difficulty walking. But this autoimmune disease of the central nervous system ...

A decade after UC San Francisco scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug’s ...

Using an animal model of multiple sclerosis (MS), researchers at the National Institutes of Health (NIH) have created a four-dimensional brain map that reveals how lesions similar to those seen in ...

Christina Applegate is revealing more about her health challenges. The "Dead to Me" star, 52, opened up about her battle with multiple sclerosis on Monday's episode of Dax Shepard's "Armchair Expert" ...