A new research paper was published in Oncotarget's, titled "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation." These isoforms have been suggested as the reason for the ...
SAN DIEGO, Oct. 17, 2023 (GLOBE NEWSWIRE) -- Recludix Pharma, a leader in platform approaches to discover inhibitors of challenging targets for inflammatory disease and cancer, announced that in a ...
A new editorial perspective was published in Oncotarget, titled "STAT3 as a biologically relevant target in H3K27M-mutant diffuse midline glioma." Pediatric H3K27M-mutant diffuse midline gliomas (DMGs ...
In a study published online in advance of print in Stem Cells, Tufts researchers report that the STAT3 gene regulates cancer stem cells in brain cancer. Cancer stem cells have many characteristics of ...
A new research paper was published in Oncotarget's Volume 14 on April 24, 2023, entitled, "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation." Signal transducer and ...
$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments
With an estimated 1.9 million new cases and more than 600,000 deaths each year, cancer remains the second most common cause of death in the U.S., trailing only heart disease. And while there are more ...
The transcription factor STAT3 is overactive in many tumors and has attracted attention as a drug target. But in vivo evidence suggesting that inhibiting STAT3 could counteract cancer has been ...
An artificial intelligence–driven transfer learning strategy enabled the discovery of a novel indolopyridine-based small ...
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