Many of the most promising medicines under development are proteins, often antibodies, to help patients fight disease. These proteins must be purified as part of the manufacturing process — a task ...

In the past 10 years, there has been great progress in the development of fluorescent proteins (FPs) to study protein movement and protein interactions. Green FP (GFP)-like proteins have been mutated ...

Tight junctions are intercellular adhesion complexes in epithelia and endothelia that control paracellular permeability. This paracellular diffusion barrier is semipermeable: it is size- and ...

Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could label proteins in millions of cells. Conventional protein-tagging methods, ...

Membrane proteins are more efficient at reaching distal dendrites than soluble proteins. Proteins are the essential substrate of learning and memory. However, while memories can last a life-time, ...

Cells continuously move materials in and out through their cell walls. Facilitated transport is one way of moving those materials without expending cellular energy. In facilitated transport, materials ...

Designing de novo proteins holds immense potential for achieving superior combinations of novel functions and mechanical properties, thereby advancing biological and engineering applications. However, ...