As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...

Researchers at the University of Gothenburg have now shown how mucus protects the small intestine in mice. In the future, this finding may lead to new ways of preventing relapse in Crohn’s disease in ...

The study, “A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts,” was published in Immunity. The team, led by Carlene L. Zindl, Ph.D., found that IL-22 ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...

The inner lining of the gut regenerates entirely every four to seven days, thanks to stem cells in the intestinal epithelium. Yet much remains shrouded in mystery regarding stem cells and what causes ...

The human small intestine is an essential organ that helps us absorb nutrients and vitamins from food. It is an average of 6 meters long and is covered with millions of villi that are separated by ...

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task. The intestine’s resident ...

Chemical and Biological Engineering PhD student Max Yavitt is the lead author on a new paper in Science Advancesthat focuses on intestinal tissue research. The work could allow researchers to control ...

Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk ...

In a study published in the journal Immunity, Carlene L. Zindl, Ph.D., and Casey T. Weaver, M.D., of the University of Alabama at Birmingham Department of Pathology show how two types of immune cells ...