San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

The rematch of the NFC Championship Game will look nothing like last season's NFC Championship Game. The 49ers rallied from a ...

Tight end George Kittle is known for being one of the most upbeat and positive personalities in the San Francisco 49ers ...

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

Detroit's defensive injuries will probably catch up to them in the postseason, but the 49ers don't look to have enough in the ...

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Videos are auto-populated by an affiliate. This site has no control over the videos that appear above. The San Francisco ...

Nick Sorensen has been heavily criticized for the underwhelming performance of the San Francisco 49ers' defense this season.

Dan Campbell and Kyle Shanahan couldn't be any different. They face each other Monday night. And technically, they're both ...

Less than a year ago, the 49ers and the Lions were the two best teams in the NFC. Now the Lions are on the verge of locking ...

More than four years after he was convicted of rape and sentenced to 15 years to life in prison, former NFL defensive lineman ...

The NFL has handed down fines to multiple San Francisco 49ers players for their actions during last weekend's game against the Miami Dolphins, per ...