Determining aqueous compound solubility has become an essential tool in the early stages of the drug discovery process. Solubility of a compound is important in the Biopharmaceutics Classification ...

The International Council for Harmonisation (ICH) last week released a presentation explaining aspects of its upcoming guideline on biopharmaceutics classification system (BCS)-based biowaivers for ...

Early adoption of the right approach to address solubility can deliver significant benefits. Currently, a significant proportion of drugs that are approved or in the development pipeline are poorly ...

The US Food and Drug Administration (FDA) on Thursday released its version of the International Council for Harmonisation (ICH) biopharmaceutics classification system (BCS) -based biowaivers guideline ...

Drug solubility can benefit from approaching solubility issues early on in the drug lifecycle. Currently, a significant proportion of drugs that are approved or in the development pipeline are poorly ...

Announcing a new article publication for BIO Integration journal. Nitrofurantoin is a BCS II drug with a low solubility and dissolution rate. Therefore, the pharmaceutical applications of ...

About 40% of marketed drugs are thought to be poorly water soluble. Development efforts might have to be redoubled, however, because between 70 and 90% of drug candidates in the pipeline are believed ...