Scientists at Pohang University of Science and Technology (POSTECH) and ShanghaiTech University have achieved a breakthrough ...

by enhancing immune tolerance. Dr. Francisco Leon, Tolerance Bio’s Co-Founder and CEO, emphasized the team’s commitment to ...

Epitope-specific immunotherapy is based on the principle of reducing the reactivity of the adaptive immune system to proinflammatory epitopes by inducing immune tolerization. A pilot phase II ...

The team concludes from this that B cells in the thymus are a necessary condition for immune tolerance regarding AQP4. "We ...

Therefore, Treg cells provide an attractive target for interventions to improve maternal immune tolerance and protect against pregnancy disorders caused by immune imbalance in at-risk women." ...

This unique function enables the education of the immune system by sampling benign dietary substances and regular microbiota ...

Regulatory T cells, which are typically anti-inflammatory, could help prevent the infant immune system from overreacting to new environmental stimuli and foods, a process known as tolerance. Zeng and ...

Tolerance Bio is led by the co-founder of a company that sold last year for $2.9 billion. Another local biopharmaceutical company has emerged from stealth mode with several million dollars in ...

The T cell repertoire is developed in the first two years of life, and the thymus then declines with age, increasing the risk of immune diseases and mortality. Tolerance Bio’s technologies aim ...

Led by industry innovator Francisco Leon, M.D., Ph.D., Tolerance Bio is developing thymus preservation, regeneration, and manipulation platforms to prevent and treat immune diseases Financing led ...