The season debut of Christian McCaffrey helped make the San Francisco 49ers offense look more like it did a year ago than it ...

The Seattle Seahawks will visit the San Francisco 49ers in a key game in the NFC West race with both teams trying to catch ...

Sportsbooks give the San Francisco 49ers (5-4) the edge when they host the Seattle Seahawks (4-5) on Sunday, November 17, ...

If Seattle wants to be the team it seeks to be, it must beat San Francisco. If Smith wants a new Seahawks deal, it’d sure ...

Star pass-catcher George Kittle and the San Francisco 49ers face the Seattle Seahawks on Sunday at 4:05 p.m. ET, at Levi’s ...

Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

The game at Tampa Bay was a virtual must-win for the previously 4-4 49ers. A loss to fall to 4-5 could have been catastrophic ...

Last time Seattle saw the 49ers, it was two less-familiar runners ripping apart the Seattle defense. The Seahawks are coming ...

The San Francisco 49ers have another important division game on Sunday, but they may have to play without two of their biggest stars.