Gut-Brain Connection. People who have CD83+ microglia in their brains also have HCMV (top left) and IgG4 (top right) in their ...

The easiest way to track down "when" in a chronic disorder like AD is with the causal quartet, those carrying disease-causing mutations in APP, PSEN1, PSEN2 and SORL1, and, as you expand, including ...

Notably, this coupling crumbles with age in mice. Restoring it not only bolstered neuronal energy reserves, but also strengthened synaptic signaling and counteracted memory loss in old animals.

While all three genotypes of mice performed similarly to wild-type animals on multiple behavioral and spatial memory tests, ...

Dennis J. Selkoe, M.D. The Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School. Co-Director, Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s ...

Sixty percent said they would take a disease-modifying treatment if it provided three additional years of independence, compared to 45 percent for a treatment offering six months. These numbers varied ...

Identifying genes that control protein levels could provide insight into disease development and progression. However, genetic analyses such as genome-wide associated studies identify regions ...

Some people’s brains age faster than average, some slower. Scientists quantify this “brain age gap” by subtracting a person’s chronological age from their brain’s biological age. Because aging brains ...