BALTIMORE - The skidding Baltimore Orioles lost to the San Francisco Giants, 5-3, Wednesday night at Camden Yards. Mike Yastrzemski homered on the game's first pitch, Michael Conforto also hit a solo shot for the Giants, who took the first two games in the series.

The Baltimore Orioles designated veteran reliever Craig Kimbrel for assignment on Wednesday afternoon. In a corresponding move, fellow righty Bryan Baker was promoted from Triple-

Depleted by injuries and entrenched in a prolonged hitting slump, the Orioles, four games behind the Yankees in the AL East with 11 to go, are desperate to regain their winning ways as they stumble to the finish of the regular season.

Baltimore Orioles relief pitcher Craig Kimbrel (46) returns to the dugout during a pitching change after he gave up six runs during the ninth inning of a baseball game against the San Francisco Giants,

It was a foregone conclusion for weeks, but the Giants officially saw their postseason chances reach zero in another heartbreaking loss.