Color is powerful driver of consumer behavior and changes can backfire, Giusti noted. In 2016, food giant General Mills removed artificial dyes from Trix cereal after requests from consumers, switching to natural sources including turmeric, strawberries and radishes.

Businesses are looking for natural alternatives, which experts say is a complex process. The "Gossip Girl" alum stepped out looking her best at the Jazz at Lincoln Center while donning a blue gown with cutouts along the bodice that accentuated her figure.

A series of studies have raised concerns by associating synthetic food colorings with health risks from hyperactivity to cancer.