BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting ...

Valvular heart disease poses an escalating global health challenge with an increasing impact on mortality and disability. This study aims to comprehensively analyze the global burden of valvular heart ...

Cardiac catheterization is a test during which flexible tubes called catheters are inserted into the heart via an artery or vein under x-ray guidance to diagnose and sometimes treat certain heart ...

Despite decades of technique refinement of transarterial embolization and the establishment of specialty referral centers, fetuses diagnosed with vein of Galen malformation continue to have high ...

Gene Ontology analysis from differentially expressed genes revealed expected changes in cell cycle, metabolism, and contractility. In addition, mRNA splicing was among the top enriched differentially ...

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association ...

In patients surviving >6 months after percutaneous coronary intervention (PCI), left ventricular ejection fraction (LVEF) at 6 to 8 months following the index PCI improved to a greater extent in ...

Currently, arrhythmias originating from perivascular areas include (1) ventricular arrhythmias from the summit region, (2) intramural outflow tract ventricular arrhythmias, and (3) atrial arrhythmias ...

The addition of dapagliflozin to standard of care in patients with heart failure across the spectrum of ejection fraction was at least of intermediate value at the undiscounted Medicare cost and may ...

Background: Participation in cardiac rehabilitation (CR) is enhanced by proximity to CR facilities and communication between inpatient and outpatient settings but may become fragmented when patients ...