Moderate-certainty evidence suggests that antioxidant vitamin and mineral supplementation (AREDS: vitamin C, E, beta-carotene, and zinc) probably slows down progression to late AMD.

We included randomised, quasi-randomised or cluster-randomised controlled trials that compared nutritional supplementation that included higher versus lower sodium supplementation in parenteral …

Dec 3, 2025 · For years, calcium supplementation has been recommended as a preventive measure, especially in populations with low dietary calcium intake. However, this updated review suggests that …

This review is an update of a previously published Cochrane Review. Overall, there was little evidence that PUFA supplementation improved symptoms of ADHD in children and adolescents.

The review found reliable evidence that taking vitamin D only, in the forms tested in the trials, is unlikely to prevent fractures. However, reliable evidence showed that vitamin D taken with additional calcium …

This is an update of a review first published in 2015. To assess if antenatal dietary supplementation with myo-inositol is safe and effective, for the mother and fetus, in preventing gestational diabetes.

Vitamin D supplementation during pregnancy may help improve maternal and neonatal health outcomes (such as fewer preterm birth and low birthweight babies) and reduce the risk of adverse pregnancy …

Is zinc supplementation effective for preventing death and disease, and for promoting growth, in children aged 6 months to 12 years and does it cause unwanted effects?

Objectives: We aimed to develop an umbrella review of systematic reviews to summarize the evidence for probiotic supplementation of adverse perinatal outcomes.

Our systematic review has demonstrated that antioxidant supplements may increase mortality. We have now updated this review. To assess the beneficial and harmful effects of antioxidant supplements for …