Nov 14, 2024 · Lithium showed a trend towards reducing suicide risk, but results were not statistically significant in the meta-analysis of seven RCTs. The study found moderate-quality …

Mar 9, 2022 · To wit, Ahrens et al 4 concluded that the mortality-reducing effect of lithium can take up to 2 years. As suicide risk varies over time, the study duration in Katz et al 1 may have …

May 18, 2025 · Pharmacological interventions, such as lithium, clozapine, and ketamine, show promise in reducing suicidality. Methods: A systematic search was conducted across Google …

An exception is growing evidence for such suicidal risk reduction with long-term lithium maintenance. This report updates and extends analyses of lith-ium treatment and suicides and …

The evidence from randomised trials of the new millennium is inconclusive and does not provide support for the belief that lithium reduces the risk of suicide or suicidal behaviour.

Aug 31, 2025 · Perhaps the most striking and consistent finding across decades of research is lithium’s effect on suicide risk. A BMJ 2013 meta-analysis (Cipriani et al.) found that lithium …

Jul 21, 2025 · However, due to the lack of evidence showing decreased suicide rates in newer agents, the superiority of Lithium in preventing suicides likely still holds true. …

Aug 25, 2025 · Evidence from randomised trials is inconclusive and does not support the idea that lithium prevents suicide or suicidal behaviour.

Nov 25, 2024 · To assess the efficacy of lithium in preventing suicide. This study was a systematic review and meta-analysis of RCTs exploring the effect of lithium on suicide.

In the last thirty years evidence has emerged to indicate that long-term treatment of bipolar disorder patients with lithium may reduce risk of suicide and attempts, with possibly similar …