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  1. Histone - Wikipedia

    Histones prevent DNA from becoming tangled and protect it from DNA damage. In addition, histones play important roles in gene regulation and DNA replication. Without histones, …

  2. Histone - National Human Genome Research Institute

    3 days ago · A histone is a protein that provides structural support for a chromosome. Each chromosome contains a long molecule of DNA, which must fit into the cell nucleus.

  3. Histone | Description, Chromatin, Structure, Functions, & Facts ...

    A histone is a type of protein that plays a critical role in the structural organization and regulation of DNA within the nucleus of eukaryotic cells.

  4. Histones types and its functions - Microbiology Notes

    Dec 31, 2019 · Group A act on histone in chromatin and involved with control of transcription. Group B act on newly synthesized histone in cytosol and are involved in nucleosomes assembly.

  5. Histone structure and nucleosome stability - PMC

    Histone proteins play essential structural and functional roles in the transition between active and inactive chromatin states. Although histones have a high degree of conservation due to …

  6. Roles of histone chaperone Nap1 and histone acetylation in

    1 day ago · Here, the authors show that histone H4 tails drive nucleosome phase separation, while histone chaperone Nap1 and H3 acetylation enhance DNA-histone dynamics to …

  7. What Are Histones in Biology? Their Structure and Function

    Aug 22, 2025 · Histones are proteins found within the nucleus of eukaryotic cells. They serve as spools around which DNA strands are wound, organizing and compacting genetic material. …

  8. Definition of histone - NCI Dictionary of Cancer Terms

    histone (HIS-tone) A type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes.

  9. What is Histones – Its types, structure, and function

    Oct 26, 2025 · There are five main types of histones. These types are divided into two main classes. The core histones are H2A, H2B, H3, and H4. The linker histones are H1 and H5 …

  10. Release and activity of histone in diseases - PMC

    Histones and their post-translational modifications have key roles in chromatin remodeling and gene transcription. Besides intranuclear functions, histones act as damage-associated …