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  1. Organoids: A new window into disease, development and discovery

    Nov 7, 2017 · Organoids can range in size from less than the width of a hair to five millimeters. There are potentially as many types of organoids as there are different tissues and organs in …

  2. Improving skin organoids | Harvard Stem Cell Institute (HSCI)

    Jun 17, 2020 · The organoids also produced Merkel cells, specialized touch-responsive cells of the skin that have been implicated in diseases such as Merkel cell carcinoma. “The inclusion …

  3. Improved human brain organoids to boost neurological disease …

    Jun 5, 2019 · These advances mean that brain organoids can now be used as viable experimental systems to study diseases in patient tissues directly, and to compare different …

  4. Brain organoids replicate key events in human brain development ...

    Sep 29, 2022 · Organoids are particularly useful for studying human development, where standard approaches used to study other animals can’t be used. But some scientists have …

  5. Different autism risk genes, same effects on brain development

    Feb 10, 2022 · When looking at organoids made from different donors, the overall changes in neural development were similar, yet the level of severity varied across individuals. The risk …

  6. Engineered miniature kidneys come of age - Harvard University

    Feb 11, 2019 · Mini-organs, called organoids, are grown in a culture dish. They contain many of the cell types and complex microarchitectures found in human organs, such as the kidney, …

  7. Modeling genetic diseases in mini-kidney organoids

    Oct 23, 2015 · The scientists then coaxed the stem cells to differentiate into mature kidney cells that self-assembled into functional organoids with the physical complications related to their …

  8. Using organoids to study early-stage lung cancer

    Sep 10, 2020 · Lung organoids made from mouse lung stem cells, with a cancer-initiating mutation in the KRAS gene (green). Credit: Antonella Dost, Boston Children’s Hospital Lung …

  9. Paola Arlotta | Harvard Stem Cell Institute (HSCI)

    A single-cell analysis of 3D models of the human cerebral cortex suggests they can be used to study important brain processes that have been difficult to investigate Adapted from the Broad …

  10. Carla Kim | Harvard Stem Cell Institute (HSCI)

    HSCI researchers develop organoids to model cancer and test potential treatments Lung cancer, the leading cancer killer in the U.S., is often missed in its earlier stages. And while recent …