Randomized controlled trials (RCT) are prospective studies that measure the effectiveness of a new intervention or treatment. Although no study is likely on its own to prove causality, …

RCTs are a fundamental methodology in modern clinical trials and are considered one of the highest-quality sources of evidence in evidence-based medicine, due to their ability to reduce …

The decision about which treatment each participant in a randomised controlled trial receives is made at random – based on chance, rather than decided by the doctor or participant. This …

randomized clinical trial (RAN-duh-mized KLIH-nih-kul TRY-ul) A study in which the participants are divided by chance into separate groups that compare different treatments or other …

Mar 14, 2025 · Discover the fundamentals of randomized controlled trials (RCTs). Learn how they're conducted, what they're used for, and how you can take part here.

A group or subgroup of participants in a clinical trial that receives a specific intervention/treatment, or no intervention, according to the trial's protocol.

In this guide, we’ll break down what a randomized clinical trial is, how it works, why randomization matters, and what patients can expect when participating in one.